Understanding current and emerging therapies for HNC

نویسنده

  • Donald R. Fleming
چکیده

STATEMENT OF NEED/PROGRAM OVERVIEW Cancers that develop in and around the oral mucosa are collectively referred to as head and neck cancers (HNCs). Although the major risk factors (tobacco use and excessive alcohol use) and most prevalent population (persons older than 60 years) are well-known, a new patient demographic is emerging. A recently identified association between HNCs, particularly oropharyngeal cancer, and human papillomavirus (HPV) infection is reflected in increased incidence of oropharyngeal cancer in younger patients with no other risk factors. In addition, HPV status has an impact on response to treatment. This activity can help oncology nurses refresh their knowledge of the risks and treatments for HNCs, and keep pace with emerging trends in patient populations and new treatment approaches.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Emerging Drug Therapies for Heart Failure

Heart failure is associated with high morbidity and mortality and is proving to be an economic burden in developing countries. A number of therapeutic agents are presently employed in heart failure; but they are not sufficient to control symptoms of heart failure. Moreover, the prevalence of chronic heart failure is progressively increasing and thus there is a continuing need to develop effecti...

متن کامل

The Cancer Stem Cell Concept in Progression of Head and Neck Cancer

Human head and neck cancer (HNC) is a highly heterogeneous disease. Understanding the biology of HNC progression is necessary for the development of novel approaches to its prevention, early detection, and treatment. A current evolutional progression model has limitations in explaining the heterogeneity observed in a single tumor nest. Accumulating evidence supports the existence of cancer stem...

متن کامل

Allergies and Risk of Head and Neck Cancer: An Original Study plus Meta-Analysis

BACKGROUND Although the relationship between allergy and cancer has been investigated extensively, the role of allergy in head and neck cancer (HNC) appears less consistent. It is not clear whether allergies can independently influence the risk of HNC in the presence of known strong environmental risk factors, including consumption of alcohol, betel quid, and cigarette. METHODS THE CURRENT PA...

متن کامل

Metabolomics of Head and Neck Cancer: A Mini-Review

Metabolomics is used in systems biology to enhance the understanding of complex disease processes, such as cancer. Head and neck cancer (HNC) is an epithelial malignancy that arises in the upper aerodigestive tract and affects more than half a million people worldwide each year. Recently, significant effort has focused on integrating multiple "omics" technologies for oncological research. In pa...

متن کامل

Pesticide Exposure and Head and Neck Cancers: A Case-Control Study in an Agricultural Region

Introduction: Causes of head and neck cancers (HNCs) are multifactorial, and few studies have investigated the association between chemical exposure and HNCs. The objective of this study was to investigate associations between HNCs, agricultural occupations, and pesticide exposure. The potential for the accumulation of pesticides in the adipose tissue of patients was also investigated.   Materi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014